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Friday, March 22, 2002:

"Bridging the gap between neuroimaging and neuroanatomy."

Dae-Shik Kim
Assistant Professor of Radiology and Neuroscience
Center for Magnetic Resonance Research
University of Minnesota Medical School


Abstract: Non-invasive cognitive neuroimaging studies based on functional MRI are of ever increasing importance for basic and clinical neurosciences. The explanatory power of fMRI could be greatly expanded, however, if the pattern of the neuronal circuitry underlying functional activation could be made visible in an equally non-invasive manner. In this study, BOLD based functional MRI in combination with Diffusion Tensor Imaging (DTI) and q-space displacement imaging were performed in the same cat visual cortex, thus providing the map of the axonal circuitry underlying visual information processing. Furthermore, the foci of fMRI activation were utilized as the seeding points for 3D DTI fiber reconstruction algorithms. The methods developed in this study will lay foundation for in vivo neuroanatomy and the ability for non-invasive longitudinal studies of brain development.
1:30pm -3:00pm, HSE 810.